The role of immune responses to peripheral myelin protein-22 (PMP22) in inflammatory and genetically determined neuropathy

Dr Carolyn Gabriel
Department of Experimental Pathology, Guy's Hospital, London
February 1996-June 1998
Charcot-Marie-Tooth syndrome is the most common sort of inherited disease of the peripheral nerves, mainly those that supply the arms and legs, causing weakness, numbness and deformities of the feet and sometimes the back of the hands. The degree to which the disease affects individuals is extremely variable, even amongst those in the same family, and this feature was the subject of investigation in this project.