An investigation into the role of neurogenesis in experimentally-induced epilepsy
Dr Lars Sundstrom & Dr Liam Gray
Department of Clinical Neurosciences, University of Southampton
October 1999 – September 2002
Department of Clinical Neurosciences, University of Southampton
October 1999 – September 2002
It has already been discovered that seizures cause an increase in the number of nerve cells in the hippocampus of the adult brain. This project aims to discover whether these new nerve cells from unstable circuits that cause the recurrent seizures of epilepsy.
It is known that young children who have had fever-induced seizures are at increased risk of developing epilepsy in adulthood. This work may direct the future development of therapies aimed at altering the proliferation rate or connectivity of these newly born nerve cells and thus prevent the development of certain types of epilepsy.
It is known that young children who have had fever-induced seizures are at increased risk of developing epilepsy in adulthood. This work may direct the future development of therapies aimed at altering the proliferation rate or connectivity of these newly born nerve cells and thus prevent the development of certain types of epilepsy.