Vascular malformations of the brain

A guide for patients and carers

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Moyamoya disease

People with Moyamoya disease have blocked arteries at the base of the brain which restricts the brain's supply of blood. The condition was first discovered in Japan and moyamoya means 'puff of smoke' in Japanese. The name describes the appearance of the very small, abnormal blood vessels that form to compensate for the blocked arteries.
It is a rare condition and tends to affect children more than adults. The exact cause is unknown but it can run in families so there is a possible hereditary risk. The main symptoms are recurring strokes or TIAs (transient ischaemic attacks). The main treatment is surgery to improve the flow of blood in the affected area.

(You might like to read our fact sheets on stroke and TIA for further information.)
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