CJD

A guide for patients and carers

How does the brain of someone with CJD differ from normal?

As mentioned above, some people with CJD have deposits or plaques of abnormal bundles of prion protein in their brains, which can be seen on examination after death.This is the most characteristic change and a definitive diagnosis is made based on finding these plaques.Typically, the brain also develops tiny holes where cells have been lost.This makes it look "spongy", hence the name spongiform encephalopathy.
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CJD

ISBN ISBN 1 901893 308
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